Part I: What's So Big About the Little Thyroid?
By Jan Cooper
This small gland is a hormone producer that affects
many parts of the body. When certain diseases or ailments are suspected
in a dog, testing for a thyrod imbalance can often lead to a more accurate
diagnosis and better treatment. The little thyroid is more often than not
one of the guilty culprits. Edward Baker, VMD, refers to the thyroid as
"the body's chief engineer." This important little gland consists of two
oval bodies located in either side of the neck. There are also tiny parts
of thyroid tissue in other areas of the chest and even around the heart.
There are two (2) forms of thyroid hormone secreted by the thyroid gland;
T3 (triiodothyronine) and T4 (thyroxine). T3 is usable thyroid hormone
while T4 must first pass through the liver and other tissues before it
can become T3, the usable thyroid. Here is where it begins to get a little
complicated, but I'll do the best I can to help simplify it. The thyroid
gland itself is regulated by two different hormones, TRH and TSH. Now,
if T4 gets too low, (remember it's not usable yet when it starts traveling
around the body) the brain tells the TRH, "Hey, wake up, go get TSH and
tell him to get to work!" Now TRH knows that TSH 'hangs out' at the nearby
Pituitary gland, and so heads straight there to find him. Well, as soon
as TSH hears about the thyroid shortage he races to the thyroid gland and
stimulates it to get busy and produce more thyroid hormone. Hence TSH stand
for THYROID STIMULATING HORMONE while TRH, being the first one to be released
into active duty, is the THYROID RELEASING HORMONE. As a consequence of
all of this, Hypothyroidism (the shortage of usable thyroid in the body)
is usually the condition seen when a thyroid imbalance is suspected. Hypothyroidism
is becoming all too common in our breed and all of our dogs should be tested.
Why do skin problems seem to go hand in hand with thyroid imbalance? In
order for our dogs to have healthy skin and coats, the cells that make
up the body must be healthy and multiply. It is not fully understood, but
thyroid hormone is essential in regulating the metabolism of each individual
cell. Whenever the cells cannot function efficiently, one of the visible
results is the skin will loose it's elasticity, and can ultimately result
in dry, crusty, scaly skin. The end result can be a dog with a very sparse
coat and a dull, almost hardened gray skin that will have a obnoxious odor.
A dog left untreated will be miserable with uncontrollable itching all
over and will further damage itself by chewing to the point of producing
raw and oozing sores, a setting ideal for bacterial infections. It is found
to be a fact that hypothyroidism is definitely associated with reduce resistance
and a greater susceptibility to bacterial infections. So if your dog develops
any type of skin ailment or a wound that does not seem to respond readily
to treatment, you might want to check for a thyroid deficiency.