Description
Dilated cardiomyopathy is a common form of cardiomyopathy.
Breed Occurrence
Dilated cardiomyopathy is most commonly seen in large breed dogs including
the Doberman Pinscher, Cocker Spaniel, Springer Spaniel, Boxer, Irish Setter,
German Shepherd Dog, Great Dane, St Bernard and Irish Wolfhound. It is
usually seen in young adult male dogs (mean age of presentation to a veterinarian
4-6 years of age).
It is also seen in young to middle-aged cats (mean age reported to
be 7.5 years) and, although all breeds can be affected, there is a higher
incidence in the Siamese, Abyssinian and Burmese breeds. In cats this form
of heart muscle disease was associated with taurine deficiency but this
is now rare.
Age prevalence
In dogs dilated cardiomyopathy can occur at any age, but in most breeds
of dog dilated cardiomyopathy occurs at a mean age of 4-6.5 years, whereas
in the Boxer it occurs slightly later (at an average age of 8 years).
In cats dilated cardiomyopathy can occur at any age with a mean age
of onset of about 7.5 years.
Sex prevalence
Males are usually affected more frequently than females with this disease,
except for Boxers and English Cocker Spaniels in which breeds studies suggest
both sexes are equally affected.
Signs
In dogs the condition can be present for a long time with no obvious
symptoms, then the clinical signs often start suddenly and include the
typical signs of heart failure including both forward and backward failure.
Commonly seen signs include difficulty breathing (called dyspnoea), a cough,
feinting, exercise intolerance and a swollen abdomen. Affected dogs often
have reduced appetite and weight loss.
Radiography
On plain radiographs all forms of dilated cardiomyopathy may show as
bilateral enlargement of the heart (called cardiomegaly) . In some breeds
there may be evidence of fluid accumulation in the lungs (called pulmonary
oedema) - Doberman and English Cocker Spaniel and cats; or free fluid in
the chest (called pleural effusion) - Dobermans.
Ultrasound (called echocardiography)
Moving (M-mode) echocardiography is the best diagnostic tool to use
to confirm the diagnosis of dilated cardiomyopathy because it clearly shows
dilation of the heart chambers with severely reduced shortening fraction
of the heart wall when the heart muscle contracts.
Treatment
Unless a specific underlying cause can be determined e.g. taurine deficiency,
L-carnitine deficiency, treatment can only be symptomatic and are the same
as those commonly used to treat heart failure.
Prognosis
The prognosis is always guarded to poor at the outset with the average
survival time being 6 months and 80% of dogs with atrial fibrillation die
in this period. Dobermans often die within days or weeks and rarely survive
for more than a year, whereas some breeds (including German Shepherds and
Great Danes) often respond well and can survive more than 2 years.
The prognosis is good for dilated cardiomyopathy associated with taurine deficiency in cats, as correction of the nutritional deficiency effectively reverses the disease.